1. Cov khoom lag luam kev lag luam
1.1 Mechanism of Action thiab Product Positioning
Quinoxyfen yog quinoline fungicide tsim los ntawm Dow AgroSciences (tam sim no ib feem ntawm Corteva). Cov khoom lag luam tau tso npe thawj zaug hauv Tebchaws Europe hauv xyoo 1996, tau pom zoo hauv Tebchaws Meskas raws li EPA's Reduced Risk Pesticide Program xyoo 1999, tau txais kev pom zoo los ntawm EU xyoo 2004, thiab tau tso cai thawj zaug rau kev siv hauv Tebchaws Europe hauv xyoo 1997. Nws yog dav siv rau zaub thiab txiv hmab txiv ntoo qoob loo xws li cherries, grapes, thiab lettuce.
Quinoxyfen belongs rau chav kawm tshuaj quinoline thiab yog ib tus tswv cuab ntawm quinoline fungicide ntawm FRAC Group 13, nrog rau cov txheej txheem tshwj xeeb ntawm kev ua haujlwm tshwj xeeb rau pawg no. Cov khoom yog ib tug tiv thaiv fungicide nrog systemic translocation zog, ua los ntawm inhibiting tsim appressoria nyob rau hauv powdery mildew fungi, yog li tiv thaiv kab mob. Quinoxyfen muaj ib tug tshwj xeeb mechanism - nws cuam tshuam nrog cov kab mob lub teeb liab transduction txoj kev. Appressorium tsim yog ib kauj ruam tseem ceeb rau powdery mildew fungi kom ua tiav invade host cells, thiab quinoxyfen qhov cuam tshuam nrog cov txheej txheem no ua rau nws yog ib qho cuab yeej tseem ceeb hauv kev tswj cov kab mob mildew.
Quinoxyfen nthuav tawm qhov tshwj xeeb ntawm kev txav mus los: tom qab daim ntawv thov, nws khi rau cov waxy txheej ntawm cov nplooj ntoo thiab txav ntawm cov ntaub so ntswg los ntawm kev tso pa qeeb, tiv thaiv nplooj thiab txiv hmab txiv ntoo qhov chaw uas tsis ncaj qha txau, tsim ib qho kev tiv thaiv txuas ntxiv. Nws muaj sijhawm ntev txog li 14 hnub thiab nag hmo zoo heev - dej nag hauv ib teev tom qab thov tsis cuam tshuam rau kev ua tau zoo. Daim ntawv thov ncua sij hawm yog 10-14 hnub ntawm grapes thiab 7-10 hnub ntawm zaub.
Hais txog lub hom phiaj cov qoob loo, quinoxyfen feem ntau yog siv los tswj cov kab mob mildew ntawm cereals (nplej, barley), txiv hmab txiv ntoo, cucurbits (melons, dib, thiab lwm yam), mangoes, txiv lws suav, thiab hops. Nyob rau hauv ltalis, ib tug 250 g / L ncua kev kawm ntawv concentrate formulation tau pom ib theem siab ntawm kev tiv thaiv thiab saj zawg zog thov tswv yim nyob rau hauv ntau haiv neeg tej yam kev mob.
1.2 Product Differentiation Advantages
Qhov tseem ceeb sib txawv ntawm qhov zoo ntawm quinoxyfen yog tshwm sim hauv peb yam:
Ua ntej,nws lub hom phiaj tshwj xeeb ua rau nws yog qhov kev xaiv tseem ceeb rau kev tswj xyuas kev sib hloov cov kev pab cuam. Tawm tsam keeb kwm yav dhau los ntawm kev ua kom tsis muaj zog rau cov kab mob fungicides tseem ceeb - nrog QoIs (FRAC 11) thiab DMIs (FRAC 3) tam sim no qhia kev tawm tsam thoob plaws - quinoxyfen lub cim tshwj xeeb ntawm kev ua haujlwm txhawb nqa nws cov nqi hloov tsis tau.
Thib ob,nws txoj kev lag luam kev lag luam tau tsom mus rau kev tswj cov kab mob powdery mildew. Cov khoom no tshwj xeeb yog tsom tawm tsam powdery mildew pathogens. Txawm hais tias qhov no txwv nws qhov dav - spectrum kev ua ub no, nws muaj lub hom phiaj zoo hauv cov cheeb tsam uas muaj cov pwm pwm siab.
Peb,nws muaj toxicity tsawg thiab ib puag ncig tus phooj ywg. Quinoxyfen muaj cov tshuaj toxicological, ib puag ncig, thiab ecotoxicological profiles. Teb Chaws Asmeskas EPA tau teev nws nyob rau hauv Txoj Kev Pabcuam Tiv Thaiv Kabmob Txom Nyem hauv xyoo 1999. Nws muaj luv luv rov- lub sijhawm nkag (12 teev), lub sijhawm sau ua ntej - 3 hnub, thiab cov khoom siv tiv thaiv tus kheej qis.
1.3 Formulation Development thiab Combination Strategies
Formulation qauv:Raws li cov ntaub ntawv xyoo 2020, Suspension Concentrate (SC) thiab Liquid (LI) yog ob hom kev tsim tshwj xeeb rau quinoxyfen. Hauv tebchaws Ltalis, 250 g / L SC tau pom tias muab kev tiv thaiv qib siab nyob rau hauv cov xwm txheej sib txawv.
Combination Product Development:Kev sib xyaw quinoxyfen nrog cov tshuaj fungicides muaj lwm cov txheej txheem ntawm kev ua haujlwm yog ib qho kev taw qhia tseem ceeb rau cov khoom muaj nqis ntxiv. Quinoxyfen-Azoxystrobin ua ke cov khoom lag luam tau tsim tawm thoob ntiaj teb thiab qhia tias kev lag luam loj hlob ntau dua li cov khoom lag luam ib leeg. Tsis tas li ntawd, quinoxyfen tuaj yeem tig nrog ntau yam fungicides, suav nrog kev sib xyaw lossis kev hloov pauv nrog triflumizole (FRAC 3), chlorothalonil (FRAC M5), thiab lwm yam, kom ncua kev txhim kho kev tiv thaiv. Nyob rau hauv cov txiv hmab txiv ntoo powdery mildew kuj saib xyuas, kev sib txuas ntawm quinoxyfen nrog benzovindiflupyr, metrafenone, thiab lwm yam khoom muab kev tswj zoo heev.
1.4 Kev Sau Npe Toj roob hauv pes thiab hloov pauv tseem ceeb
Cov kev sau npe tseem ceeb rau kev txhim kho quinoxyfen sawv cev rau qhov hloov pauv tseem ceeb tshaj plaws hauv kev ua lag luam toj roob hauv pes.
EU tus txheej xwm sau npe:Tsis pom zoo lawm.
Kev sau npe nyob rau hauv lwm cheeb tsam:Quinoxyfen tam sim no tseem tau tso cai siv ntau lub tebchaws, suav nrog Australia, Chile, thiab Tebchaws Meskas. Hauv Canada, Lub Chaw Tswj Xyuas Kab Tsuag (PMRA) muaj cuaj cov ntaub ntawv ntawm cov ntawv thov uas muaj quinoxyfen, nrog rau QUINTEC FUNGICIDE cov khoom lag luam coj tus lej sau npe 29755. Hauv Teb Chaws Asmeskas kev lag luam, Dow AgroSciences 'Quintec® cov khoom tseem siv dav, nrog rau re- nkag lub sijhawm ntawm 12 hnub ua ntej, {4} qis dua, kev tiv thaiv cov khoom siv.
Sau npe toj roob hauv pes hauv Suav teb:Shaanxi Hengrun Linong Biotechnology Co., Ltd.
2. Kev Tsim Kho Kev Lag Luam
2.1 Kev Lag Luam Thoob Ntiaj Teb Loj thiab Kev Ntsuas Kev Sib Tw
Kev lag luam thoob ntiaj teb loj rau quinoxyfen sib txawv ntau ntawm cov txheej txheem kev txheeb cais thiab kev ntsuas qhov ntev, vim yog cov khoom lag luam patent txheej xwm hloov pauv, kev hloov pauv hauv cov khoom lag luam, thiab kev tshem tawm tsis ntev los no los ntawm EU.
Xyoo 2019, thaum Nissan Chemical Corporation tau txais tag nrho cov khoom lag luam quinoxyfen (xws li cov khoom lag luam xws li Quintec® thiab Fortress™) los ntawm Corteva, Inc., kev lag luam - qib ntsuas ntawm cov khoom kab yog kwv yees li US $ 280 lab, nrog rau lub lag luam tseem ceeb yog US hmoov pwm tswj kev lag luam. Qhov kev ntsuas no sawv cev rau cov ntaub ntawv pov thawj kev lag luam taw qhia rau tag nrho cov nqi lag luam ntawm quinoxyfen cov khoom lag luam raws li tau tshaj tawm hauv cov peev txheej pej xeem.
2.2 Kev Ntsuas Kev Lag Luam Hauv Kev Lag Luam Kev Lag Luam
Thaum Lub Kaum Ob Hlis 2019, Nissan Chemical tshaj tawm qhov tau txais quinoxyfen cov khoom lag luam los ntawm Corteva. Qhov kev sib pauv tau them rau txhua lub npe, suav nrog Quintec® thiab Fortress ™, nrog rau cov khoom lag luam muaj feem xyuam. Quinoxyfen yog ib qho kev tiv thaiv fungicide zoo tiv thaiv cov kab mob mildew hauv cereals, txiv hmab txiv ntoo, txiv hmab txiv ntoo pob zeb, thiab zaub xws li cucurbits. Nws muaj qhov tshwj xeeb ntawm kev ua thiab tau ua lag luam thoob ntiaj teb feem ntau yog ib qho -cov khoom lag luam nquag Quintec® thiab raws li cov khoom sib xyaw Arius ™ (quinoxyfen + myclobutanil). Lub khw tseem ceeb yog Tebchaws Meskas, nrog tus nqi lag luam kwv yees li US $ 280 lab. Tom qab qhov tau txais, Nissan Chemical koom tes nrog Gowan Company, lub hauv paus hauv Arizona, Tebchaws Asmeskas, los koom ua ke quinoxyfen rau hauv Gowan cov chaw lag luam hauv Tebchaws Meskas, Mexico, thiab Chile.
2.3 Cov qauv kev lag luam hauv cheeb tsam thiab kev txhim kho tseem ceeb
(1) Kev hloov pauv loj hauv EU kev lag luam
Kev tshem tawm quinoxyfen los ntawm EU kev ua lag luam tau muaj kev cuam tshuam loj heev rau cov khoom siv thoob ntiaj teb -xav tau kev xav tau. Kev tawm ntawm EU sawv cev rau qhov kev hloov pauv loj tshaj plaws hauv lub ntiaj teb quinoxyfen kev ua lag luam.
(2) Teb Chaws Asmeskas kev lag luam - core muag cheeb tsam
Tebchaws Asmeskas yog thaj chaw muag khoom tseem ceeb rau quinoxyfen thiab yog thawj lub lag luam raug soj ntsuam thaum xyoo 2019 tau. Quintec® yog tib lub npe FRAC Group 13 fungicide nyob rau hauv Teb Chaws Asmeskas lag luam, dav siv rau powdery mildew tswj ntawm ntau yam qoob loo xws li txiv hmab txiv ntoo, cucurbits, pob zeb txiv hmab txiv ntoo, strawberries, thiab peppers. Gowan Company tam sim no yog tus tsim tshwj xeeb ntawm Quintec® hauv Tebchaws Meskas, Mexico, thiab Chile.
(3) Australia kev lag luam - thaj chaw loj hlob
Australia tam sim no yog ib qho kev lag luam loj tshaj plaws rau quinoxyfen. Thaum xyoo 2023-2024, APVMA (Australian Pesticides and Veterinary Medicines Authority) tau tshaj tawm cov ntawv tso cai siv thaum muaj xwm txheej ceev rau kev tswj cov hmoov nplej hmoov nplej. GRDC (Grains Research and Development Corporation)-Kev tshawb nrhiav nyiaj txiag tau lees paub tias quinoxyfen (cov khoom lag luam muaj 250 g / L quinoxyfen, piv txwv li, Legend®, daim ntawv tso cai naj npawb PER93197), ua ke nrog metrafenone (Vivando®, PER93198) thiab proquinazid (Talendo wheat, PER93198) hmoov tswj. Qhov no yog thawj zaug quinoxyfen tau tso cai siv rau hauv Australian hom qoob mog, tom qab nws ntev - tso cai nyob rau hauv cov qoob loo xws li txiv hmab txiv ntoo (Legend fungicide pom zoo rau cov txiv hmab txiv ntoo powdery mildew tswj nyob rau hauv 2002).
(4) Lwm lub khw
Quinoxyfen tam sim no tswj hwm kev sau npe hauv ntau lub tebchaws, suav nrog Chile thiab Israel, thiab tseem raug muag los ntawm Gowan Company cov kev faib tawm.
2.4 Kev sib tw toj roob hauv pes
Tus tsim tawm thawj:Dow AgroSciences (tom qab muab tso rau hauv Corteva Agriscience) yog thawj tus tsim tawm ntawm quinoxyfen, tuav cov npe lag luam tseem ceeb xws li Quintec® thiab Fortress ™, nrog rau cov khoom sib xyaw Arius ™ (quinoxyfen + myclobutanil).
Cov khoom xa tuaj:Thaum Lub Kaum Ob Hlis 2019, Nissan Chemical tau txais tag nrho quinoxyfen cov khoom lag luam los ntawm Corteva. Tom qab ntawd, Nissan Chemical koom tes nrog Gowan Tuam Txhab los koom ua ke quinoxyfen rau hauv Gowan cov chaw lag luam hauv Tebchaws Meskas, Mexico, thiab Chile. Lub tuam txhab Gowan tam sim no yog tus tsim tshwj xeeb ntawm Quintec® hauv cov khw no.
Nkag mus rau Suav lag luam:Xyoo 2024, quinoxyfen tau txais nws thawj zaug xa tawm -tsuas yog kev tso npe hauv Suav teb, kos npe nkag ntawm Shaanxi Hengrun Linong Biotechnology Co., Ltd. rau hauv lub ntiaj teb quinoxyfen cov saw hlau, feem ntau koom nrog thoob ntiaj teb cov khoom siv los ntawm kev xa tawm cov khoom siv thiab cov qauv.
Lwm tus neeg koom nrog:Lwm cov neeg koom nrog thoob ntiaj teb suav nrog Arysta LifeScience, ntawm lwm tus, uas faib cov khoom lag luam quinoxyfen hauv Tebchaws Europe thiab lwm thaj chaw.
2.5 Market Trend Summary
Kev ua lag luam quinoxyfen tam sim no nyob rau theem hloov pauv:
Cov yam ntxwv zoo:Tus nqi tswj kev tiv thaiv tau muab los ntawm nws cov txheej txheem tshwj xeeb ntawm kev ua haujlwm (FRAC Group 13) yog qhov tseem ceeb hauv kev sib hloov; qhov tseem ceeb thoob ntiaj teb kev thov rau kev tswj cov kab mob mildew txuas ntxiv mus; kev thov los ntawm siab- cov qoob loo muaj txiaj ntsig (txiv hmab txiv ntoo, zaub, txiv hmab txiv ntoo, thiab lwm yam) tseem nyob ruaj khov; xyoo 2019 tau txais cov khoom lag luam los ntawm Nissan Chemical ntawm kev lag luam tus nqi kwv yees li US $ 280 lab qhia kev lag luam paub txog nws cov nqi lag luam; kev thov rau quinoxyfen yog loj hlob nyob rau hauv cov lag luam tawm tshiab xws li Australia vim yog kev tswj hwm kev xav tau; Kev nkag mus ntawm Tuam Tshoj cov lag luam rau hauv cov khoom lag luam tuaj yeem pab nthuav dav thoob ntiaj teb.
Yam tsis zoo:Lub EU tshem tawm yog qhov loj tshaj qhov tsis zoo sib txawv, ua rau muaj kev sib cog lus tseem ceeb hauv tag nrho cov lag luam thoob ntiaj teb.
Kev taw qhia yav tom ntej:Kev loj hlob ntawm kev lag luam yav tom ntej yuav vam khom ntau dua rau thaj chaw uas quinoxyfen tseem muaj, xws li North America, Australia, thiab Latin America. Kev txhim kho cov khoom sib xyaw ua ke nrog cov tshuaj fungicides uas muaj lwm cov txheej txheem ntawm kev ua thiab kev sib hloov siv nyob rau hauv Integrated Pest Management (IPM) cov kev pab cuam yuav yog lub ntsiab lus tseem ceeb rau cov khoom muaj nqis ntxiv. Ua raws li Tuam Tshoj tso cai rau kev xa tawm-tsuas yog sau npe, Suav cov lag luam yuav tsum tau ua lub luag haujlwm tseem ceeb hauv ntiaj teb cov khoom lag luam.
3. Cov lus pom zoo
(1) Cov khoom lag luam zoo:
Ua ntej tsim cov khoom sib xyaw ua ke ntawm quinoxyfen nrog cov tshuaj fungicides muaj lwm yam kev ua haujlwm los daws cov teeb meem tiv thaiv thiab nthuav dav cov kab mob tswj hwm. Muab hais tias quinoxyfen tshwj xeeb tsom rau cov kab mob mildew, kev sib txuas nrog DMI cov khoom (xws li, tebuconazole), QoI cov khoom (xws li, azoxystrobin), thiab lwm yam tuaj yeem muab kev dav dua - spectrum tiv thaiv kab mob. Tsis tas li ntawd, tshawb nrhiav cov lus qhia txog tus phooj ywg zoo ib puag ncig xws li kua thiab ncua kev kawm emulsions los txhim kho cov khoom sib tw.
(2) Kev lag luam zoo:
Tsom ntsoov rau cov cheeb tsam thiab ntu nram qab no: Ua ntej, North American lag luam - US EPA tau teev npe quinoxyfen nyob rau hauv nws Cov Kev Pab Cuam Tshuam Txom Nyem hauv xyoo 1999, muab lub hauv paus kev lag luam ruaj khov, thiab Quintec® hom tau zoo- tsim. Thib ob, Australian kev ua lag luam - GRDC kev tshawb fawb thiab APVMA daim ntawv tso cai qhia txog kev thov hauv zos rau quinoxyfen, ua rau nws yog ib qho tseem ceeb ntawm kev lag luam loj hlob. Thib peb, siab - cov qoob loo muaj txiaj ntsig (txiv hmab txiv ntoo, zaub, txiv hmab txiv ntoo, thiab lwm yam) - qhov uas cov neeg cog qoob loo muaj kev txaus siab them thiab cov nqi tsev siab.
(3) Supply chain Strategy:
Thawj qhov kev xa tawm -tsuas yog sau npe rau quinoxyfen hauv Suav teb xyoo 2024 yog qhov kev nkag ntawm Shaanxi Hengrun Linong Biotechnology Co., Ltd. rau hauv lub ntiaj teb quinoxyfen cov saw hlau. Nyob rau tib lub sijhawm, kev saib xyuas yuav tsum tau them rau cov tuam txhab kev sib tw hom lag luam thiab cov txiaj ntsig zoo channel, siv cov tswv yim sib tw sib txawv.
